Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation analysis of CTNNB1 gene and the ras pathway genes KRAS, NRAS, BRAF, and PIK3CA in eyelid sebaceous carcinomas.

Pathology, research and practice - 1 Jun 2017

Kwon Mi Jung, Nam Eun Sook, Cho Seong Jin, Park Hye-Rim, Min Soo Kee, Seo Jinwon, Choe Ji-Young

Abstract excerpt

Sebaceous carcinoma (SC) represents a rare, aggressive eyelid malignancy with poor prognosis and is a possible component of Muir-Torre syndrome. However, genetic features as driver mutations or potential therapeutic targets are not fully elucidated. Recent a few studies have shown that SCs have concurrently multiple mutations including RAS/RAF/MAPK and PI3K/Akt pathways via next-generation sequencing in western...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to GTP Phosphohydrolases

Share to Membrane Proteins

Share to Microsatellite Instability

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 28551389
DOI: 10.1016/j.prp.2017.02.015

Genes

BRAF
NRAS
CTNNB1
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation analysis of CTNNB1 gene and the ras pathway genes KRAS, NRAS, BRAF, and PIK3CA in eyelid sebaceous carcinomas.PMID 28551389Read ↗

Molecular landscape of eyelid sebaceous gland carcinoma: A comprehensive review.Semantic proximity Read ↗

Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma.Semantic proximity Read ↗

Suspected Molecular Links in Sebaceous Gland Carcinoma of the Eyelid: A scoping reviewSemantic proximity Read ↗

[Sebaceous gland carcinoma of the eyelid co-occurred with other tumors: a report of four cases].Semantic proximity Read ↗

NGS Analysis Confirms Common TP53 and RB1 Mutations, and Suggests MYC Amplification in Ocular Adnexal Sebaceous Carcinomas.Semantic proximity Read ↗

UV-independent p53 mutations in sebaceous carcinoma of the eyelid.Semantic proximity Read ↗

Distinct Pathways in the Pathogenesis of Sebaceous Carcinomas Implicated by Differentially Expressed MicroRNAsSemantic proximity Read ↗

Identification of somatic KRAS mutation in a Korean baby with nevus sebaceus syndrome.Semantic proximity Read ↗

miRNA-200c and miRNA-141 as potential prognostic biomarkers and regulators of epithelial-mesenchymal transition in eyelid sebaceous gland carcinomaSemantic proximity Read ↗

The DNA mismatch repair system in sebaceous tumors: an update on the genetics and workup of Muir-Torre syndrome.Semantic proximity Read ↗

KRAS, HRAS and EGFR Mutations in Sporadic Sebaceous Gland Hyperplasia.Semantic proximity Read ↗

TERT promoter mutation in sebaceous neoplasms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.