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Article

Genetic analysis of VCP and WASH complex genes in a German cohort of sporadic ALS-FTD patients.

Neurobiology of aging - 1 Aug 2017

Türk Matthias, Schröder Rolf, Khuller Katharina, Hofmann Andreas, Berwanger Carolin, Ludolph Albert C, Dekomien Gabriele, Müller Kathrin, Weishaupt Jochen H, Thiel Christian T, Clemen Christoph S

Abstract excerpt

Mutations of the human valosin-containing protein, p97 (VCP) and Wiskott-Aldrich syndrome protein and SCAR homolog (WASH) complex genes cause motor neuron and cognitive impairment disorders. Here, we analyzed a cohort of German patients with sporadic amyotrophic lateral sclerosis and frontotemporal lobar degeneration comorbidity (ALS/FTD) for VCP and WASH complex gene mutations. Next-generation panel sequencing...

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Source

Identifiers

PMID: 28551275
DOI: 10.1016/j.neurobiolaging.2017.04.023

Genes

VCP
CAPZA1
CAPZB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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