Article
Independent validation of body fluid-specific CpG markers and construction of a robust multiplex assay.
Forensic science international. Genetics - 1 Jul 2017
Holtkötter Hannah, Beyer Vanessa, Schwender Kristina, Glaub Alina, Johann Kristina Schulze, Schürenkamp Marianne, Sibbing Ursula, Banken Sabrina, Wiegand Peter, Pfeiffer Heidi, Dennany Lynn, Vennemann Marielle, Vennemann Marielle
Abstract excerpt
Potential forensic use of tissue-specific DNA methylation markers has recently been discussed for the identification of the biological source of a stain. In this study 13 promising markers were evaluated to identify suitable candidate markers for the development of a robust and reliable multiplex assay. The results of this study suggest that a combination of only four highly informative markers will be enough for...
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