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Article

Myeloid neoplasms with germ line RUNX1 mutation.

International journal of hematology - 1 Aug 2017

Hayashi Yoshihiro, Harada Yuka, Huang Gang, Harada Hironori

Abstract excerpt

Familial platelet disorder with propensity to myeloid malignancies (FPD/AML) is an autosomal dominant disorder characterized by quantitative and/or qualitative platelet defects with a tendency to develop a variety of hematological malignancies. Heterozygous germ line mutations in the RUNX1 gene are responsible genetic events for FPD/AML. Notably, about half of individuals in the family with germ line mutations in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28534116
DOI: 10.1007/s12185-017-2258-5

Genes

RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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