Article
Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures.
Behavioural processes - 1 Sept 2017
Lewon Matthew, Peters Christina M, Van Ry Pam M, Burkin Dean J, Hunter Kenneth W, Hayes Linda J
Abstract excerpt
The mdx mouse is an important nonhuman model for Duchenne muscular dystrophy (DMD) research. Characterizing the behavioral traits of the strain relative to congenic wild-type (WT) mice may enhance our understanding of the cognitive deficits observed in some humans with DMD and contribute to treatment development and evaluation. In this paper we report the results of a number of experiments comparing the behavior...
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