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Article

[Frequency of Helicobacter pylori nitroreductase RdxA mutations for metronidazole activation in a population in the Cauca Department, Colombia].

Biomedica : revista del Instituto Nacional de Salud - 1 Jun 2017

Acosta Claudia Patricia, Quiroga Andrés Javier, Sierra Carlos H, Trespalacios Alba Alicia

Abstract excerpt

INTRODUCTION: Resistance to metronidazole is a key factor associated with Helicobacter pylori treatment failure. Even though resistance is mostly associated with RdxA nitroreductase mutations, studies of this H. pylori protein in Popayán (Colombia) are still incipient. OBJECTIVE: To evaluate the frequency of mutations in the RdxA nitroreductase in a population of patients with H. pylori-positive gastrointestinal...

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Identifiers

PMID: 28527283
DOI: 10.7705/biomedica.v37i2.3007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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