Article
Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell lines.
PloS one - 1 Jan 2017
Mondejar Rufino, Pérez Cristina, Onaindia Arantza, Martinez Nerea, González-Rincón Julia, Pisonero Helena, Vaqué Jose Pedro, Cereceda Laura, Santibañez Miguel, Sánchez-Beato Margarita, Piris Miguel Angel
Abstract excerpt
T and NK-cell lymphoma is a collection of aggressive disorders with unfavorable outcome, in which targeted treatments are still at a preliminary phase. To gain deeper insights into the deregulated mechanisms promoting this disease, we searched a panel of 31 representative T-cell and 2 NK-cell lymphoma/leukemia cell lines for predictive markers of response to targeted therapy. To this end, targeted sequencing was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.