Article
Application of Panel-Based Tests for Inherited Risk of Cancer.
Annual review of genomics and human genetics - 31 Aug 2017
Shah Payal D, Nathanson Katherine L
Abstract excerpt
Next-generation or massively parallel sequencing has transformed the landscape of genetic testing for cancer susceptibility. Panel-based genetic tests evaluate multiple genes simultaneously and rapidly. Because these tests are frequently offered in clinical settings, understanding their clinical validity and utility is critical. When evaluating the inherited risk of breast and ovarian cancers, panel-based tests...
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