Article
Next Generation Sequencing uncovers within-host differences in the genetic diversity of Cryptosporidium gp60 subtypes.
International journal for parasitology - 1 Sept 2017
Zahedi Alireza, Gofton Alexander William, Jian Fuchun, Paparini Andrea, Oskam Charlotte, Ball Andrew, Robertson Ian, Ryan Una
Abstract excerpt
The extent of within-host genetic diversity of parasites has implications for our understanding of the epidemiology, disease severity and evolution of parasite virulence. As with many other species, our understanding of the within-host diversity of the enteric parasite Cryptosporidium is changing. The present study compared Sanger and Next Generation Sequencing of glycoprotein 60 (gp60) amplicons from...
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