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Article

Extensive intra-host genetic diversity uncovered in Cryptosporidium parvum using Next Generation Sequencing.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2013

Grinberg A, Biggs P J, Dukkipati V S R, George T T

Abstract excerpt

The theory about the Cryptosporidium life cycle predicts genetic diversity of sporozoites within the host. Nevertheless, the Cryptosporidium intra-host genetic diversity is difficult to study using conventional Sanger sequencing or electrophoretic resolution of amplicons, due to the methods' inability to resolve mixtures of templates. We analysed the within-isolate genetic diversity of two Cryptosporidium parvum...

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Identifiers

PMID: 22981926
DOI: 10.1016/j.meegid.2012.08.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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