Article
Valine/isoleucine variants drive selective pressure in the VP1 sequence of EV-A71 enteroviruses.
BMC infectious diseases - 8 May 2017
Duy Nghia Ngu, Huong Le Thi Thanh, Ravel Patrice, Huong Le Thi Song, Dwivedi Ankit, Sessions October Michael, Hou Yan'An, Chua Robert, Kister Guilhem, Afelt Aneta, Moulia Catherine, Gubler Duane J, Thiem Vu Dinh, Thanh Nguyen Thi Hien, Devaux Christian, Duong Tran Nhu, Hien Nguyen Tran, Cornillot Emmanuel, Gavotte Laurent, Frutos Roger
Abstract excerpt
BACKGROUND: In 2011-2012, Northern Vietnam experienced its first large scale hand foot and mouth disease (HFMD) epidemic. In 2011, a major HFMD epidemic was also reported in South Vietnam with fatal cases. This 2011-2012 outbreak was the first one to occur in North Vietnam providing grounds to study the etiology, origin and dynamic of the disease. We report here the analysis of the VP1 gene of strains isolated...
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