Article
Physiological Phenotyping for Personalized Therapy of Uncontrolled Hypertension in Africa.
American journal of hypertension - 1 Sept 2017
Akintunde Adeseye, Nondi Justus, Gogo Kennedy, Jones Erika S W, Rayner Brian L, Hackam Daniel G, Spence J David
Abstract excerpt
OBJECTIVES: African and African American hypertensives tend to retain salt and water, with lower levels of plasma renin and more resistant hypertension. We tested the hypothesis that physiological phenotyping with plasma renin and aldosterone would improve blood pressure control in uncontrolled hypertensives in Africa. METHODS: Patients at hypertension clinics in Nigeria, Kenya, and South Africa with a systolic...
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