Article
The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease.
Alimentary pharmacology & therapeutics - 1 Jul 2017
Ananthakrishnan A N, Sakuraba A, Barnes E L, Pekow J, Raffals L, Long M D, Sandler R S
Abstract excerpt
BACKGROUND: The impact of combination therapy on disease-related morbidity in patients with established Crohn's disease (CD) or ulcerative colitis (UC) remains to be well-defined. AIM: To examine the effect of combination therapy on disease outcomes in CD and UC. METHODS: Using a multicenter prospective cohort, we classified CD and UC patients as being on monotherapy with anti-TNF or on combination with an...
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