Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP450 genotype and aggressive behavior on selective serotonin reuptake inhibitors.

Pharmacogenomics - 1 May 2017

Ekhart Corine, Matic Maja, Kant Agnes, van Puijenbroek Eugène, Schaik Ron van

Abstract excerpt

AIM: Genetic variants for selective serotonin reuptake inhibitor (SSRI) metabolizing enzymes have been hypothesized to be a risk factor for aggression as adverse drug effect of SSRIs. Our aim was to assess the possible involvement of these polymorphisms on aggression when using SSRIs. MATERIALS & METHODS: A retrospective noninterventional case-control study was performed on 18 cases. The genetic profile of two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aggression
Share to Case-Control Studies
Share to Cytochrome P-450 CYP2C19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Cytochrome P-450 Enzyme System

Share to Depressive Disorder

Share to Genetic Variation

Share to Selective Serotonin Reuptake Inhibitors

Source

Identifiers

PMID: 28470107
DOI: 10.2217/pgs-2017-0197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP450 genotype and aggressive behavior on selective serotonin reuptake inhibitors.PMID 28470107Read ↗

Effect of Cytochrome P450 polymorphism on the action and metabolism of selective serotonin reuptake inhibitors.Semantic proximity Read ↗

Genotyping of patients treated with selective serotonin reuptake inhibitors.Semantic proximity Read ↗

Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors.Semantic proximity Read ↗

Serotonin Transporter Gene Polymorphisms and Selective Serotonin Reuptake Inhibitor Tolerability: Review of Pharmacogenetic EvidenceSemantic proximity Read ↗

Effect of Polymorphisms on the Pharmacokinetics, Pharmacodynamics and Safety of Sertraline in Healthy Volunteers.Semantic proximity Read ↗

Investigation of CYP3A4*22 polymorphism effects on the depressed treatment by citalopram and sertralineSemantic proximity Read ↗

Serotonin transporter polymorphism and bleeding time during SSRI therapy.Semantic proximity Read ↗

Risk factors for extrapyramidal symptoms during treatment with selective serotonin reuptake inhibitors, including cytochrome P-450 enzyme, and serotonin and dopamine transporter and receptor polymorphisms.Semantic proximity Read ↗

Serotonin transporter polymorphisms and side effects in antidepressant therapy--a pilot study.Semantic proximity Read ↗

Update on the biological treatment of aggression.Semantic proximity Read ↗

Clinical implications of selective serotonin reuptake inhibitors-selective serotonin norepinephrine reuptake inhibitors pharmacogenetics during pregnancy and lactation.Semantic proximity Read ↗

Monoamine Oxidase A gene polymorphisms and self reported aggressive behaviour in a Pakistani ethnic group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.