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Article

Relationship between fibrillin-1 genotype and severity of cardiovascular involvement in Marfan syndrome.

Heart (British Cardiac Society) - 1 Nov 2017

Franken Romy, Teixido-Tura Gisela, Brion Maria, Forteza Alberto, Rodriguez-Palomares Jose, Gutierrez Laura, Garcia Dorado David, Pals Gerard, Mulder Barbara Jm, Evangelista Artur

Abstract excerpt

BACKGROUND: The effect of FBN1 mutation type on the severity of cardiovascular manifestations in patients with Marfan syndrome (MFS) has been reported with disparity results. OBJECTIVES: This study aims to determine the impact of the FBN1 mutation type on aortic diameters, aortic dilation rates and on cardiovascular events (ie, aortic dissection and cardiovascular mortality). METHODS: MFS patients with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28468757
DOI: 10.1136/heartjnl-2016-310631

Genes

FBN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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