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Article

1,25-Dihydroxyvitamin D3 suppresses gastric cancer cell growth through VDR- and mutant p53-mediated induction of p21.

Life sciences - 15 Jun 2017

Li Mingxing, Li Longfei, Zhang Lin, Hu Wei, Shen Jing, Xiao Zhangang, Wu Xu, Chan Franky Leung, Cho Chi Hin

Abstract excerpt

AIMS: Previous studies have indicated that vitamin D deficiency correlates with cancer risk and vitamin D potentiates antitumor effects in a variety of cancers. The antitumor effect of vitamin D on gastric cancer was rarely studied. We aimed to investigate the antitumor effect of vitamin D on gastric cancer and underlying mechanisms. MAIN METHODS: We investigated the antitumor activity of the active form of...

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Source

Identifiers

PMID: 28465245
DOI: 10.1016/j.lfs.2017.04.021

Genes

VDR
CDK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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