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Article

Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.

The Journal of clinical endocrinology and metabolism - 1 Aug 2017

Billings Liana K, Jablonski Kathleen A, Warner A Sofia, Cheng Yu-Chien, McAteer Jarred B, Tipton Laura, Shuldiner Alan R, Ehrmann David A, Manning Alisa K, Dabelea Dana, Franks Paul W, Kahn Steven E, Pollin Toni I, Knowler William C, Altshuler David, Florez Jose C

Abstract excerpt

Context: Variation in genes that cause maturity-onset diabetes of the young (MODY) has been associated with diabetes incidence and glycemic traits. Objectives: This study aimed to determine whether genetic variation in MODY genes leads to differential responses to insulin-sensitizing interventions. Design and Setting: This was a secondary analysis of a multicenter, randomized clinical trial, the Diabetes...

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Identifiers

PMID: 28453780
DOI: 10.1210/jc.2016-3429
PMCID: PMC5546852

Genes

NEUROD1

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