Article
GWAS analysis of treatment resistant schizophrenia: interaction effect of childhood trauma.
Pharmacogenomics - 1 May 2017
Koga Arthur, Bani-Fatemi Ali, Hettige Nuwan, Borlido Carol, Zai Clement, Strauss John, Gerretsen Philip, Graff Ariel, Remington Gary, De Luca Vincenzo
Abstract excerpt
AIMS: In the current study, we aimed to compare the prevalence of adverse lifetime events in treatment resistant and non-treatment resistant schizophrenia in a genome-wide association study. MATERIALS & METHODS: Our sample consisted of 84 Caucasian participants with schizophrenia spectrum disorders, assessed cross-sectionally to collect information regarding drug effectiveness and childhood trauma. Using a...
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