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Article

Retinal changes in the Tg-SwDI mouse model of Alzheimer's disease.

Neuroscience - 23 Jun 2017

Oliveira-Souza Fred G, DeRamus Marci L, van Groen Thomas, Lambert Alexis E, Bolding Mark S, Strang Christianne E

Abstract excerpt

Alzheimer's disease (AD), a debilitating neurodegenerative illness, is characterized by neuronal cell loss, mental deficits, and abnormalities in several neurotransmitter and protein systems. AD is also associated with visual disturbances, but their causes remain unidentified. We hypothesize that the visual disturbances stem from retinal changes, particularly changes in the retinal cholinergic system, and that...

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Identifiers

PMID: 28450267
DOI: 10.1016/j.neuroscience.2017.04.021
PMCID: PMC5495115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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