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Inferring Allele Frequency Trajectories from Ancient DNA Indicates That Selection on a Chicken Gene Coincided with Changes in Medieval Husbandry Practices.

Molecular biology and evolution - 1 Aug 2017

Loog Liisa, Thomas Mark G, Barnett Ross, Allen Richard, Sykes Naomi, Paxinos Ptolemaios D, Lebrasseur Ophélie, Dobney Keith, Peters Joris, Manica Andrea, Larson Greger, Eriksson Anders

Abstract excerpt

Ancient DNA provides an opportunity to infer the drivers of natural selection by linking allele frequency changes to temporal shifts in environment or cultural practices. However, analyses have often been hampered by uneven sampling and uncertainties in sample dating, as well as being confounded by demographic processes. Here, we present a Bayesian statistical framework for quantifying the timing and strength of...

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PMID: 28444234
DOI: 10.1093/molbev/msx142
PMCID: PMC5850110

Genes

TSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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