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The CRISPR/Cas9 system: Their delivery, in vivo and ex vivo applications and clinical development by startups

25 Apr 2017

Abstract excerpt

The CRISPR/Cas9 gene editing system was originally derived from the prokaryotic adaptive immune system mediated by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated proteins (Cas). The system has been successfully applied to genome editing in eukaryotes and has contributed to remarkable advances in the life sciences, in areas ranging from agriculture to genetic disease...

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PMID: 28440027
DOI: 10.1002/btpr.2484

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