Article
Chlamydia spp. development is differentially altered by treatment with the LpxC inhibitor LPC-011.
BMC microbiology - 24 Apr 2017
Cram Erik D, Rockey Daniel D, Dolan Brian P
Abstract excerpt
BACKGROUND: Chlamydia species are obligate intracellular bacteria that infect a broad range of mammalian hosts. Members of related genera are pathogens of a variety of vertebrate and invertebrate species. Despite the diversity of Chlamydia, all species contain an outer membrane lipooligosaccharide (LOS) that is comprised of a genus-conserved, and genus-defining, trisaccharide 3-deoxy-D-manno-oct-2-ulosonic acid...
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