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White spot syndrome virus VP28 specific double-stranded RNA provides protection through a highly focused siRNA population

13 Apr 2017

Abstract excerpt

Several studies have demonstrated that injection of double-stranded RNAs (dsRNA) homologous to mRNA for the white spot syndrome virus (WSSV) viral protein 28 (VP28) can induce protection in shrimp against WSSV through RNA interference (RNAi). In comparison to shrimp injected with either PBS or a green fluorescent protein (GFP) nonspecific dsRNA, we obtained nearly complete protection against WSSV infection in...

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PMID: 28432348
DOI: 10.1038/s41598-017-01181-w

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