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Article

Emerging roles of macrosatellite repeats in genome organization and disease development

20 Apr 2017

Abstract excerpt

Abundant repetitive DNA sequences are an enigmatic part of the human genome. Despite increasing evidence on the functionality of DNA repeats, their biologic role is still elusive and under frequent debate. Macrosatellites are the largest of the tandem DNA repeats, located on one or multiple chromosomes. The contribution of macrosatellites to genome regulation and human health was demonstrated for the D4Z4...

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PMID: 28426282
DOI: 10.1080/15592294.2017.1318235

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