Article
Genome-wide analysis of macrosatellite repeat copy number variation in worldwide populations: evidence for differences and commonalities in size distributions and size restrictions.
BMC genomics - 4 Mar 2013
Schaap Mireille, Lemmers Richard J L F, Maassen Roel, van der Vliet Patrick J, Hoogerheide Lennart F, van Dijk Herman K, Baştürk Nalan, de Knijff Peter, van der Maarel Silvère M
Abstract excerpt
BACKGROUND: Macrosatellite repeats (MSRs), usually spanning hundreds of kilobases of genomic DNA, comprise a significant proportion of the human genome. Because of their highly polymorphic nature, MSRs represent an extreme example of copy number variation, but their structure and function is largely understudied. Here, we describe a detailed study of six autosomal and two X chromosomal MSRs among 270 HapMap...
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