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Article

STAT3 genetic variant, alone and in combination with STAT5b polymorphism, contributes to breast cancer risk and clinical outcomes.

Medical oncology (Northwood, London, England) - 1 Jan 2015

Zhao Haishan, Wang Zhe, Wu Huizhe, Xiao Qinghuan, Yao Weifan, Wang Enhua, Liu Yong, Wei Minjie

Abstract excerpt

The genetic or abnormal activation of signal transducer and activator of transcription (STATs) family proteins play an important role with regard to disease progression in variety of human malignancies, yet no data are available for candidate gene and breast cancer (BC) risk. To address this, we investigate the correlation between STAT3, STAT5b polymorphisms and BC susceptibility, clinicopathological parameters,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25487443
DOI: 10.1007/s12032-014-0375-z

Genes

STAT3

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