Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-set analysis shows association between FMRP targets and autism spectrum disorder.

European journal of human genetics : EJHG - 1 Jun 2017

Jansen Arija, Dieleman Gwen C, Smit August B, Verhage Matthijs, Verhulst Frank C, Polderman Tinca J C, Posthuma Danielle

Abstract excerpt

Autism spectrum disorder (ASD) is a heterogeneous group of disorders characterized by problems with social interaction, communication, and repetitive and restricted behavior. Despite its high heritability and the substantial progress made in elucidating genetic associations, the corresponding biological mechanisms are largely unknown. Our objective is to investigate the contribution of common genetic variation to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autism Spectrum Disorder
Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Genes, Mitochondrial

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Synaptic Transmission

Source

Open in PubMed Open full text

Identifiers

PMID: 28422133
DOI: 10.1038/ejhg.2017.55
PMCID: PMC5520067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-set analysis shows association between FMRP targets and autism spectrum disorder.PMID 28422133Read ↗

The roles of FMRP-regulated genes in autism spectrum disorder: single- and multiple-hit genetic etiologies.Semantic proximity Read ↗

Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders.Semantic proximity Read ↗

Genome-wide characterization of genetic and functional dysregulation in autism spectrum disorderSemantic proximity Read ↗

Convergence and Divergence of Common and Rare Variants of Autism Spectrum Disorders in Tissue-specific Pathways and Gene NetworksSemantic proximity Read ↗

Convergence and divergence of genes informed by common and rare variants of autism spectrum disorders in tissue-specific pathways and gene networks.Semantic proximity Read ↗

Systematic Reconstruction of Autism Biology with Multi-Level Whole Exome AnalysisSemantic proximity Read ↗

Database-assisted screening of autism spectrum disorder related gene set.Semantic proximity Read ↗

A brain region-specific predictive gene map for autism derived by profiling a reference gene set.Semantic proximity Read ↗

Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia.Semantic proximity Read ↗

A systematic review of common genetic variation and biological pathways in autism spectrum disorder.Semantic proximity Read ↗

Searching for convergent pathways in autism spectrum disorders: insights from human brain transcriptome studies.Semantic proximity Read ↗

Coupling of autism genes to tissue-wide expression and dysfunction of synapse, calcium signalling and transcriptional regulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.