Article
Regulation of antibiotic-resistance by non-coding RNAs in bacteria.
Current opinion in microbiology - 1 Apr 2017
Dar Daniel, Sorek Rotem
Abstract excerpt
Antibiotic resistance genes are commonly regulated by sophisticated mechanisms that activate gene expression in response to antibiotic exposure. Growing evidence suggest that cis-acting non-coding RNAs play a major role in regulating the expression of many resistance genes, specifically those which counteract the effects of translation-inhibiting antibiotics. These ncRNAs reside in the 5'UTR of the regulated...
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