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Article

Variable clinical course of identical twin neonates with Alström syndrome presenting coincidentally with dilated cardiomyopathy.

American journal of medical genetics. Part A - 1 Jun 2017

Hollander Seth A, Alsaleh Norah, Ruzhnikov Maura, Jensen Kristen, Rosenthal David N, Stevenson David A, Manning Melanie

Abstract excerpt

Alström Syndrome (AS) is a rare autosomal recessive disorder caused by mutations in the ALMS1 gene. We report monozygotic twin infants who presented concurrently with symptoms of congestive heart failure (CHF) due to dilated cardiomyopathy (DCM). Following their initial presentation, one twin improved both echocardiographically and functionally while the other twin showed a progressive decline in ventricular...

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Source

Identifiers

PMID: 28407410
DOI: 10.1002/ajmg.a.38200

Genes

ALMS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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