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In Silico Analysis of L1/L2 Sequences of Human Papillomaviruses: Implication for Universal Vaccine Design.

Viral immunology - 1 Apr 2017

Ghorban Hosseini Nazila, Tebianian Majid, Farhadi Ayoub, Hossein Khani Ali, Rahimi Arian, Mortazavi Mojtaba, Hosseini Seyed Younes, Taghizadeh Morteza, Rezaei Mahsa, Mahdavi Mehdi

Abstract excerpt

The aim of this study was to design a multiepitope universal vaccine for major human papillomavirus (HPV) structural proteins, L1/L2, by bioinformatics models. For this purpose, we predicted the most probable immunogenic epitopes of L1 and L2 from common high-risk HPV 16, 18, 31, and 45 beside high prevalent type 6 and 11 based on BCPREDS defaulted model, while solvent accessibility of structure was extrapolated....

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PMID: 28388355
DOI: 10.1089/vim.2016.0142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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