Article
Exome sequence genotype imputation in globally diverse hexaploid wheat accessions.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Jul 2017
Shi Fan, Tibbits Josquin, Pasam Raj K, Kay Pippa, Wong Debbie, Petkowski Joanna, Forrest Kerrie L, Hayes Ben J, Akhunova Alina, Davies John, Webb Steven, Spangenberg German C, Akhunov Eduard, Hayden Matthew J, Daetwyler Hans D
Abstract excerpt
KEY MESSAGE: Imputing genotypes from the 90K SNP chip to exome sequence in wheat was moderately accurate. We investigated the factors that affect imputation and propose several strategies to improve accuracy. Imputing genetic marker genotypes from low to high density has been proposed as a cost-effective strategy to increase the power of downstream analyses (e.g. genome-wide association studies and genomic...
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