Article
Development of the Wheat Practical Haplotype Graph database as a resource for genotyping data storage and genotype imputation.
G3 (Bethesda, Md.) - 4 Feb 2022
Jordan Katherine W, Bradbury Peter J, Miller Zachary R, Nyine Moses, He Fei, Fraser Max, Anderson Jim, Mason Esten, Katz Andrew, Pearce Stephen, Carter Arron H, Prather Samuel, Pumphrey Michael, Chen Jianli, Cook Jason, Liu Shuyu, Rudd Jackie C, Wang Zhen, Chu Chenggen, Ibrahim Amir M H, Turkus Jonathan, Olson Eric, Nagarajan Ragupathi, Carver Brett, Yan Liuling, Taagen Ellie, Sorrells Mark, Ward Brian, Ren Jie, Akhunova Alina, Bai Guihua, Bowden Robert, Fiedler Jason, Faris Justin, Dubcovsky Jorge, Guttieri Mary, Brown-Guedira Gina, Buckler Ed, Jannink Jean-Luc, Akhunov Eduard D
Abstract excerpt
To improve the efficiency of high-density genotype data storage and imputation in bread wheat (Triticum aestivum L.), we applied the Practical Haplotype Graph (PHG) tool. The Wheat PHG database was built using whole-exome capture sequencing data from a diverse set of 65 wheat accessions. Population haplotypes were inferred for the reference genome intervals defined by the boundaries of the high-quality gene...
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