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M. tuberculosis Hypothetical Proteins and Proteins of Unknown Function: Hope for Exploring Novel Resistance Mechanisms as well as Future Target of Drug Resistance

21 Mar 2017

Abstract excerpt

Drug resistance in tuberculosis predominantly, mono-resistance, multi drug resistance, extensively drug resistance and totally drug resistance have emerged as a major problem in the chemotherapy of tuberculosis. Failures of first and second line anti-tuberculosis drugs treatment leads to emergence of resistant M.tuberculosis. Few genes are reported as the principal targets of the resistance and apart from the...

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PMID: 28377758
DOI: 10.3389/fmicb.2017.00465

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