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Article

Extinct type of human parvovirus B19 persists in tonsillar B cells.

Nature communications - 4 Apr 2017

Pyöriä Lari, Toppinen Mari, Mäntylä Elina, Hedman Lea, Aaltonen Leena-Maija, Vihinen-Ranta Maija, Ilmarinen Taru, Söderlund-Venermo Maria, Hedman Klaus, Perdomo Maria F

Abstract excerpt

Parvovirus B19 (B19V) DNA persists lifelong in human tissues, but the cell type harbouring it remains unclear. We here explore B19V DNA distribution in B, T and monocyte cell lineages of recently excised tonsillar tissues from 77 individuals with an age range of 2-69 years. We show that B19V DNA is most frequent and abundant among B cells, and within them we find a B19V genotype that vanished from circulation >40...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28374737
DOI: 10.1038/ncomms14930
PMCID: PMC5382274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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