Ancient human parvovirus B19 in Eurasia reveals its long-term association with humans.

doi:10.1073/pnas.1804921115

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Article

Ancient human parvovirus B19 in Eurasia reveals its long-term association with humans.

Proceedings of the National Academy of Sciences of the United States of America - 17 Jul 2018

Mühlemann Barbara, Margaryan Ashot, Damgaard Peter de Barros, Allentoft Morten E, Vinner Lasse, Hansen Anders J, Weber Andrzej, Bazaliiskii Vladimir I, Molak Martyna, Arneborg Jette, Bogdanowicz Wieslaw, Falys Ceri, Sablin Mikhail, Smrčka Václav, Sten Sabine, Tashbaeva Kadicha, Lynnerup Niels, Sikora Martin, Smith Derek J, Fouchier Ron A M, Drosten Christian, Sjögren Karl-Göran, Kristiansen Kristian, Willerslev Eske, Jones Terry C

Abstract excerpt

Human parvovirus B19 (B19V) is a ubiquitous human pathogen associated with a number of conditions, such as fifth disease in children and arthritis and arthralgias in adults. B19V is thought to evolve exceptionally rapidly among DNA viruses, with substitution rates previously estimated to be closer to those typical of RNA viruses. On the basis of genetic sequences up to ∼70 years of age, the most recent common...

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PMID: 29967156
DOI: 10.1073/pnas.1804921115
PMCID: PMC6055166

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