Article
Promoter polymorphisms of the TIM-4 gene are correlated with disease activity in patients with systemic lupus erythematosus.
International journal of immunogenetics - 1 Jun 2017
Liu B, Liu W, Wang R, Shu Q, Zhang X, Fan X, Zhang Q, Liang X, Ma C, Gao L
Abstract excerpt
Although the TIM gene family plays important roles in immune responses, little is known about TIM regulation in the development of systemic lupus erythematosus (SLE). This study aimed to investigate the association of two TIM-4 single nucleotide polymorphisms (SNPs) rs6874202 (-1419G>A) and rs62382402 (-1609G>A) with SLE susceptibility in a Chinese Han population. The results showed no significant differences...
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