Article
Daclatasvir/asunaprevir/beclabuvir, all-oral, fixed-dose combination for patients with chronic hepatitis C virus genotype 1.
Journal of gastroenterology and hepatology - 1 Dec 2017
Kao Jia-Horng, Yu Ming-Lung, Peng Cheng-Yuan, Heo Jeong, Chu Chi-Jen, Chang Ting-Tsung, Lee Youn-Jae, Hu Tsung-Hui, Yoon Ki Tae, Paik Seung Woon, Lim Young Suk, Ahn Sang Hoon, Isakov Vasily, McPhee Fiona, Hu Wenhua, Scott Swenson Eugene, Yin Philip D, Treitel Michelle
Abstract excerpt
BACKGROUND AND AIM: This multinational (Taiwan, South Korea, Russia) phase 3 study evaluated the all-oral, ribavirin-free, fixed-dose combination (DCV-TRIO) of daclatasvir (NS5A inhibitor) 30 mg, asunaprevir (NS3 inhibitor) 200 mg, and beclabuvir (NS5B inhibitor) 75 mg, in patients with chronic hepatitis C virus genotype-1 infection, with or without compensated cirrhosis. METHODS: UNITY-4 (NCT02170727) was an...
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