Article
First Report of Hb Limassol [β8(A5)Lys→Asn; HBB: c.27G>C] from Odisha, India.
Hemoglobin - 1 Nov 2016
Meher Satyabrata, Dehury Snehadhini, Jana Arpita, Bhattacharya Subhra, Patel Amrita, Das Kishalaya, Patel Siris, Sarkar Biswanath, Mohanty Pradeep Kumar
Abstract excerpt
In this short report, we describe the clinical presentation of a rare hemoglobin (Hb) variant, Hb Limassol [β8(A5)Lys→Asn; HBB: c.27G>C] with a faster electrophoretic mobility than Hb A and that elutes in the P3 window on cation exchange high performance liquid chromatography (HPLC). This sequence variation at codon 8 (AAG>AAC) of the HBB gene was found in the four heterozygous cases, all of whom were clinically...
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