Article
Effects of osteopontin-enriched formula on lymphocyte subsets in the first 6 months of life: a randomized controlled trial.
Pediatric research - 1 Jul 2017
West Christina E, Kvistgaard Anne Staudt, Peerson Janet M, Donovan Sharon M, Peng Yong-Mei, Lönnerdal Bo
Abstract excerpt
BackgroundHuman milk is rich in osteopontin (OPN), which has immunomodulatory functions.MethodsIn a randomized controlled trial, standard formula (SF) and the same formula with 65 mg of OPN/L (F65) or 130 mg of OPN/L (F130), representing ~50 and 100% of the OPN concentration in human milk, were compared. We examined frequencies and composition of peripheral blood immune cells by four-color immunoflow cytometry of...
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