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Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells

1 Mar 2017

Abstract excerpt

One major obstacle in cancer therapy is chemoresistance leading to tumor recurrence and metastasis. Cancer stem cells, in particular glioblastoma stem cells, are highly resistant to chemotherapy, radiation, and immune recognition. In case of immune recognition, several survival mechanisms including, regulation of autophagy, proteases, and cell surface major histocompatibility complex class I molecules, are found...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28347245
DOI: 10.1177/1010428317692227

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