Article
Telomere Length, Oxidative Stress, Inflammation and BDNF Levels in Siblings of Patients with Bipolar Disorder: Implications for Accelerated Cellular Aging.
The international journal of neuropsychopharmacology - 1 Jun 2017
Vasconcelos-Moreno Mirela Paiva, Fries Gabriel Rodrigo, Gubert Carolina, Dos Santos Bárbara Tietböhl Martins Quadros, Fijtman Adam, Sartori Juliana, Ferrari Pamela, Grun Lucas Kich, Parisi Mariana Migliorini, Guma Fátima Theresinha Costa Rodrigues, Barbé-Tuana Florencia Maria, Kapczinski Flávio, Rosa Adriane Ribeiro, Yatham Lakshmi N, Kauer-Sant'Anna Marcia
Abstract excerpt
Background: Growing evidence supports the existence of neurobiological trait abnormalities in individuals at genetic risk for bipolar disorder. The aim of this study was to examine potential differences in brain-derived neurotrophic factor, cytokines, oxidative stress, and telomere length markers between patients with bipolar disorder, their siblings, and healthy controls. Methods: Thirty-six patients with...
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