Article
Presence of both heterogeneous vancomycin-intermediate resistance and β-lactam antibiotic-induced vancomycin resistance phenotypes is associated with the outcome in methicillin-resistant Staphylococcus aureus bloodstream infection.
Scandinavian journal of infectious diseases - 1 Mar 2013
Takata Tohru, Miyazaki Motoyasu, Futo Maki, Hara Shuji, Shiotsuka Shouichi, Kamimura Hidetoshi, Yoshimura Hisae, Matsunaga Akira, Nishida Takeshi, Ishikura Hiroyasu, Ishikawa Takahiko, Tamura Kazuo, Tsuji Brian T
Abstract excerpt
BACKGROUND: Although the individual expression of heterogeneous vancomycin-intermediate resistance (hVISA) and β-lactam antibiotic-induced vancomycin resistance (BIVR) phenotypes has been associated with treatment failure and recurrence in methicillin-resistant Staphylococcus aureus (MRSA) infections, the effect of the co-expression of these phenotypic profiles on clinical outcome has not been fully elucidated....
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