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Article

Effects of Antenatal Maternal Depressive Symptoms and Socio-Economic Status on Neonatal Brain Development are Modulated by Genetic Risk.

Cerebral cortex (New York, N.Y. : 1991) - 1 May 2017

Qiu Anqi, Shen Mojun, Buss Claudia, Chong Yap-Seng, Kwek Kenneth, Saw Seang-Mei, Gluckman Peter D, Wadhwa Pathik D, Entringer Sonja, Styner Martin, Karnani Neerja, Heim Christine M, O'Donnell Kieran J, Holbrook Joanna D, Fortier Marielle V, Meaney Michael J

Abstract excerpt

This study included 168 and 85 mother-infant dyads from Asian and United States of America cohorts to examine whether a genomic profile risk score for major depressive disorder (GPRSMDD) moderates the association between antenatal maternal depressive symptoms (or socio-economic status, SES) and fetal neurodevelopment, and to identify candidate biological processes underlying such association. Both cohorts showed...

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Identifiers

PMID: 28334351
DOI: 10.1093/cercor/bhx065
PMCID: PMC6057508

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