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Article

Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System

31 Mar 2017

Abstract excerpt

BACKGROUND: The complexity of spermatogenesis makes development of appropriate in vitro testis models challenging. A novel in vitro mouse testis culture system has been reported but not yet evaluated as an alternative model for male reproductive toxicity testing. We assessed the effects of media composition on sperm differentiation and testis morphology of cultured mouse testis fragments. METHODS: Testes from...

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PMID: 28398669
DOI: 10.1002/bdr2.1002

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