Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enterolactone Induces G1-phase Cell Cycle Arrest in Nonsmall Cell Lung Cancer Cells by Downregulating Cyclins and Cyclin-dependent Kinases

21 Mar 2017

Abstract excerpt

Flaxseed is a rich source of the plant lignan secoisolariciresinol diglucoside (SDG), which is metabolized into mammalian lignans enterodiol (ED) and enterolactone (EL) in the digestive tract. The anticancer properties of these lignans have been demonstrated for various cancer types, but have not been studied for lung cancer. In this study, we investigated the anticancer effects of EL for several nonsmall cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Liver Disease Diagnosis and Treatment
Share to Phytoestrogen effects and research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28323486
DOI: 10.1080/01635581.2017.1296169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enterolactone Induces G1-phase Cell Cycle Arrest in Nonsmall Cell Lung Cancer Cells by Downregulating Cyclins and Cyclin-dependent KinasesPMID 28323486Read ↗

Lutein inhibits tumor progression through the ATR /Chk1/p53 signaling pathway in non‐small cell lung cancerSemantic proximity Read ↗

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma proteinSemantic proximity Read ↗

Natural Flavonoids Targeting Deregulated Cell Cycle Progression in Cancer CellsSemantic proximity Read ↗

Antineoplastic Effects of Erufosine on Small and Non-Small Lung Cancer Cells Through Induction of Apoptosis and Cell Cycle ArrestSemantic proximity Read ↗

Lutein Inhibits Cell Growth and Activates Apoptosis via the PI3K/AKT/mTOR Signaling Pathway in A549 Human Non-Small-Cell Lung Cancer CellsSemantic proximity Read ↗

Silibinin inhibits human nonsmall cell lung cancer cell growth through cell‐cycle arrest by modulating expression and function of key cell‐cycle regulatorsSemantic proximity Read ↗

Sesamin, a lignan of sesame, down‐regulates cyclin D1 protein expression in human tumor cellsSemantic proximity Read ↗

Liriopesides B induces apoptosis and cell cycle arrest in human non‑small cell lung cancer cellsSemantic proximity Read ↗

β‐Cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non‐small‐cell lung cancer cells and up‐regulates retinoic acid receptor β expressionSemantic proximity Read ↗

Retinoblastoma gene-independent G1 phase arrest by flavone, phosphatidylinositol 3-kinase inhibitor, and histone deacetylase inhibitor.Semantic proximity Read ↗

Resibufogenin Induces G1-Phase Arrest through the Proteasomal Degradation of Cyclin D1 in Human Malignant Tumor CellsSemantic proximity Read ↗

Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.