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Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment

20 Mar 2017

Abstract excerpt

Orthomyxoviruses are an important family of RNA viruses, which include the various influenza viruses. Despite global efforts to eradicate orthomyxoviral pathogens, these infections remain pervasive. One such orthomyxovirus, infectious salmon anemia virus (ISAV), spreads easily throughout farmed and wild salmonids, constituting a significant economic burden. ISAV entry requires the interplay of the virion-attached...

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PMID: 28320973
DOI: 10.1073/pnas.1617993114

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