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Article

Intrinsic gene changes determine the successful establishment of stable renal cancer cell lines from tumor tissue.

International journal of cancer - 1 Jun 2017

Feng Hailiang, Zhang Yu, Liu Kan, Zhu Yan, Yang Zhenli, Zhang Xu, Liu Yuqin

Abstract excerpt

Human tumor cell lines, especially those with complete data and follow-up, are important tools in tumor biological studies. Clear cell renal cell cancer (ccRCC) is not sensitive to radiotherapy or chemotherapy, and treatment of patients with distant metastasis relies on targeted therapy. Here, we report the establishment of seven new ccRCC stable cell lines that were continuously cultured for more than 20...

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Source

Identifiers

PMID: 28256713
DOI: 10.1002/ijc.30674

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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