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Excess of genomic defects in a woolly mammoth on Wrangel island.

PLoS genetics - 1 Mar 2017

Rogers Rebekah L, Slatkin Montgomery

Abstract excerpt

Woolly mammoths (Mammuthus primigenius) populated Siberia, Beringia, and North America during the Pleistocene and early Holocene. Recent breakthroughs in ancient DNA sequencing have allowed for complete genome sequencing for two specimens of woolly mammoths (Palkopoulou et al. 2015). One mammoth specimen is from a mainland population 45,000 years ago when mammoths were plentiful. The second, a 4300 yr old...

Topics

Animals
DNA, Ancient
Evolution, Molecular
Fossils
Genome
Genomics
Islands
Mammoths
Mutation
Russia
Sequence Analysis, DNA
Time Factors

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PMID: 28253255
DOI: 10.1371/journal.pgen.1006601
PMCID: PMC5333797

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FOXQ1

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