Article
Phenotyping of myocardial fibrosis in hypertensive patients with heart failure. Influence on clinical outcome.
Journal of hypertension - 1 Apr 2017
Ravassa Susana, López Begoña, Querejeta Ramón, Echegaray Kattalin, San José Gorka, Moreno María U, Beaumont Francisco J, González Arantxa, Díez Javier
Abstract excerpt
OBJECTIVE: Myocardial fibrosis is associated with alterations in the cross-linking and deposition of collagen type I (CCL and CD, respectively). We aimed to evaluate whether the combination of circulating biomarkers of CCL [the carboxy-terminal telopeptide of collagen type I to matrix metalloproteinase-1 ratio (CITP : MMP-1)] and CD [the carboxy-terminal propeptide of procollagen type I (PICP)] identifies...
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