Article
Maternal common variant rs2305957 spanning PLK4 is associated with blastocyst formation and early recurrent miscarriage.
Fertility and sterility - 1 Apr 2017
Zhang Qian, Li Guangyu, Zhang Lei, Sun Xiaohe, Zhang Dandan, Lu Juanjuan, Ma Jinlong, Yan Junhao, Chen Zi-Jiang
Abstract excerpt
OBJECTIVE: To investigate whether the common variant rs2305957 spanning PLK4 (Polo-like kinase 4) confers risk to embryo development in Northern Chinese Han (CHN) women. DESIGN: Genetic association study. SETTING: University hospital. PATIENT(S): A total of 2,015 infertile women who underwent in vitro fertilization (IVF), 530 women with early recurrent miscarriage (ERM), and 600 fertile control women in the CHN...
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